This study advances SV characterization by integrating linear and graph based calling methods to create the first population-scale catalogue of SVs using long-reads.

1,019 samples from twentysix 1000 Genomes Project populations were sequenced to intermediate coverage using Oxford Nanopore Technologies (ONT). Linear and graph-based approaches for SV analysis were integrated via pangenome graph-augmentation, to uncover 167,291 sequence-resolved SVs, 164,571 of which were successfully phased.

This work is described in Long-read sequencing and structural variant characterization in 1,019 samples from the 1000 Genomes Project by Schloissnig, Pani et al

Data available includes:

• Alignments to GRCh38
• Alignments to T2T-CHM13
• Alignments to the HPRC year-1 minigraph pangenome graph
• A Giggles genotyped call set of 167,291 SVs
• A SHAPEIT5 phased integrated call set of 164,571 SVs

Files can be browsed by sample, population and data type below. Files are available on the IGSR FTP and via the public Globus Collection EMBL-EBI Public Data, path /1000g/ftp/data_collections/1KG_ONT_VIENNA/