This policy refers to all the data associated with the Human Genome Structural Variation Consortium (HGSVC) to create a high quality catalog of structural variation using various sequencing approaches.
All data in the HGSVC data collection on the FTP site and data portal are part of the project.
Continuing the philosophy of the 1000 Genomes Project, the data producers for this Project will release the Project data quickly, prior to publication, in the expectation that they will be valuable for many researchers. In keeping with Fort Lauderdale principles, data users may use the data for many studies, but are expected to allow the data producers to make the first presentations and to publish the first paper with global analyses of the data.
The Project plans to publish global analyses of the sequence data and quality, structural variants, STRs and microsatellites and haplotypes and LD patterns, population genetic phenomena such as population comparisons, mutation rates, and signals of selection, and functional annotations, as well as analyses of regions of general interest such as HLA. Talks, posters, and papers on all such analyses are to be published first by the Human Genome Structural Variation Consortium, by approved presenters on behalf of the Project, with the group as author. When the first major Project paper on these analyses is published, then researchers inside and outside the Project are free to present and publish using the Project data for these and other analyses.
Groups within the Project may make presentations and publish papers on more extensive analyses of topics to be included in the main analysis presentations and papers, coincident with the main Project analysis presentations and papers. The major points would be included in the main Project presentations and papers, but these additional presentations and papers allow more focused discussion of methods and results. The author list would include the Consortium.
Researchers who have used small amounts of Project data (<=one chromosome or chromosomal regions not of general interest) may present methods development posters, talks, and papers that include these data prior to the first major Project paper, without needing Project approval or authorship, although the Project should be acknowledged. Methods presentations or papers on global analyses or analyses using large amounts of Project data, on topics that the Consortium plans to examine, would be similar to large-scale analyses of Project data: researchers within the Project may make presentations or submit papers at the same time as the main Project presentations and papers, and others could do so after the Project publishes the first major analysis paper.
Researchers may present and publish on use of Project data in specific chromosome regions (that are not of general interest) or as summaries (such as the total number of variants) for disease studies without Project approval, prior to the first major Project paper being published. The Project should not be listed as an author.
Researchers may use Project data as controls or additional information for comparisons with their samples from people with particular diseases or from other populations, prior to the major Project paper being published, as long as the analyses that the Project plans to do are not included. These are not Project studies, and the Project should not be listed as an author.
Researchers who have questions about whether they may make presentations or submit papers using Project data on any paper can contact us.
Please email info@1000genomes.org to with any questions about either the index files or the data reuse policy.